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Free, publicly-accessible full text available October 23, 2026
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Patidar, Krutika; Ford_Versypt, Ashlee N (, American Journal of Physiology-Renal Physiology)This work provides a novel analysis of signaling cross talk between macrophages and glomerular endothelial cells in the early stage of diabetic kidney disease. A logic-based mathematical modeling approach identified vital signaling molecules and interactions that regulate glucose-mediated inflammation in glomerular endothelial cells and cause endothelial dysfunction in the diabetic kidney. Simulated interactions among vascular endothelial growth factor receptor 1, nitric oxide, and calcium significantly affected the intercellular junction proteins between glomerular endothelial cells.more » « lessFree, publicly-accessible full text available July 1, 2026
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Patidar, Krutika; Deng, Jennifer H.; Mitchell, Cassie S.; Ford_Versypt, Ashlee N (, International Journal of Molecular Sciences)
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